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No effect of n-3 long chain polyunsaturated fatty acid (EPA and DHA) supplementation
Project Code: N05038
University of Bristol
Rogers, P ; Appleton, K; Kessler, D; Peters, T; Gunnell, D; Hayward, R; Heatherley, S; Christian, L; McNaughton, S; Ness, A
Background: Low dietary intakes of the n-3 LCPUFAs eicosapentaenoic acid (EPA) and decosahexaenoic acid (DHA) are thought to be associated with increased risk for variety of health outcomes, including some psychiatric disorders. Evidence from observational and intervention studies for a role of n-3 LCPUFAs in depression is mixed, with some support for a benefit of EPA and/or DHA in major depressive illness.
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