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The effect of cruciferous vegetable dietary intervention on human urinary metabonomic profile
Project Code: T01048
Department of biomolecular medicine, Faculty of Medicine, Imperial College, London
This project used metabonomic techniques to carry out analyses on archived urine samples collected as part of an earlier FSA funded dietary intervention study (project T01009). It set out to determine the effect of a cruciferous vegetable dietary intervention in humans on the urinary metabolite profile (cruciferous vegetables include some of the most common types of vegetables eaten, including cabbage, cauliflower, turnip, rapeseed and radish). From the urinary metabolite profiles, the study tried to identify urinary biomarkers associated with cruciferous vegetable intervention. It also aimed to determine the effect of meat consumption and caffeine intake on the individuals’ normal urinary metabolite profile and investigated the effect cruciferous vegetable consumption had on the meat and caffeine alterations of profile.
The results of this project make it possible to identify metabolic pathways modified by cruciferous vegetable intervention.
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